Alzheimer's study points to good sleep as a possible tool to resist it
The link is to the abstract info on the academic research url. There is also an article on WSJ which discusses it, but it is similarly behind a paywall.
The core of it is that they studied the use of a sleep drug for how it affected the presence of other chemicals in the spinal fluid which correlate to Alzheimer's.
The study is far from a smoking gun, but is just another arrow that can be interpreted. The big thing is that if it proves true, then it becomes a concrete thing that people can do on their own to try and lessen risks of it. The same way that exercise is something individuals can do to resist diabetes and other similar risks, sleep could be that for dementia and other neurological issues. Neither guarantee safety, but they offer some additional benefit.
We will see how further studies result in this area, but for now - it's a good reason to try and not skimp on sleep (this is a note to myself.)
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Study shows that electrical impulse treatment to senior brains could help resist effects of Alzheimers
A new study with the following dense title, "Long-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation" is pretty hard to grok and I bounced off of it. I heard about it from this article on Verge.com.
The Abstract:
The development of technologies to protect or enhance memory in older people is an enduring goal of translational medicine. Here we describe repetitive (4-day) transcranial alternating current stimulation (tACS) protocols for the selective, sustainable enhancement of auditory–verbal working memory and long-term memory in 65–88-year-old people. Modulation of synchronous low-frequency, but not high-frequency, activity in parietal cortex preferentially improved working memory on day 3 and day 4 and 1?month after intervention, whereas modulation of synchronous high-frequency, but not low-frequency, activity in prefrontal cortex preferentially improved long-term memory on days 2–4 and 1?month after intervention. The rate of memory improvements over 4?days predicted the size of memory benefits 1?month later. Individuals with lower baseline cognitive function experienced larger, more enduring memory improvements. Our findings demonstrate that the plasticity of the aging brain can be selectively and sustainably exploited using repetitive and highly focalized neuromodulation grounded in spatiospectral parameters of memory-specific cortical circuitry.
Will be curious to see if further studies come out of this and perhaps a new treatment for seniors becomes standard in an effort to improve memory recall for them.
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New dementia prevention method may be behavioral, not prescribed
The influential Lancet Commission began leading the modifiable-risk-factor movement in 2017. A panel of doctors, epidemiologists and public health experts reviewed and analyzed hundreds of high-quality studies to identify nine risk factors accounting for much of the world’s dementia: high blood pressure, lower education levels, impaired hearing, smoking, obesity, depression, physical inactivity, diabetes and low levels of social contact.
In 2020, the commission added three: excessive alcohol consumption, traumatic brain injuries and air pollution. The commission calculated that 40% of dementia cases worldwide could theoretically be prevented or delayed if those factors were eliminated.
Regarding the 'alcohol consumption' bit, my cursory research suggest this is "excessive alcohol consumption" such that it causes brain damage. As we can see by those who partake in a Mediterranean diet with its red wine, overall they seem to fair well in this arena.
The article also mentions that vision loss might be added in the future. Sensory loss makes sense, your brain has less inputs to keep it active.
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